Peptide sequence: LGSSRPTPIL DLDIQRHLTH FSLITHGFGT PAICAALSTF QTVLSEMLNY
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activating enhancer binding protein 2 beta-like 1; Activating enhancer-binding protein 2-delta; AP-2 like; AP2-delta; TFAP2D; transcription factor AP-2 beta (activating enhancer binding protein 2 beta)-like 1; transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)-like 1; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta
Gene Aliases: TFAP2BL1; TFAP2D
UniProt ID: (Human) Q7Z6R9
Entrez Gene ID: (Human) 83741
Molecular Function: transcription factor