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Bethyl Laboratories
TFIP11 Polyclonal Antibody
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Product Details
IHC-00705
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1 and 50 of Human tuftelin interacting protein 11.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla and Chimpanzee
Target Information
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Septin and tuftelin-interacting protein 1; STIP-1; Tuftelin-interacting protein 11; tuftelin-interacting protein 33; Tuftelin-interacting protein 39; tuftelin-interacting protein, 39 kD
Gene Aliases: 2810002G02Rik; AF097181; AW046167; bK445C9.6; hNtr1; HSPC006; NTR1; Spp382; Srr1; STIP; TFIP11; TIP33; TIP39
UniProt ID: (Human) Q9UBB9, (Mouse) Q9ERA6
Entrez Gene ID: (Human) 24144, (Mouse) 54723
spliceosomal complex disassembly
mRNA splicing, via spliceosome
regulation of transcription, DNA-templated
RNA processing
biomineral tissue development
negative regulation of protein complex assembly
protection from non-homologous end joining at telomere
negative regulation of protein binding
negative regulation of DNA ligase activity
negative regulation of double-strand break repair via nonhomologous end joining
mRNA processing
RNA splicing
cell differentiation
extracellular matrix organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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