In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) TFPI-2, rhTFPI-1, and recombinant mouse TFPI-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
TFPI2 may play a role in the regulation of plasmin-mediated matrix remodeling. It inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. TFPI2 has no effect on thrombin.
Protein Aliases: PP5FLJ21164; TFPI-2; TFPI-2REF1; Tissue factor pathway inhibitor 2
Gene Aliases: AV000670; PP5/TFPI-2; Tfpi2
UniProt ID: (Mouse) O35536
Entrez Gene ID: (Mouse) 21789
Molecular Function: protease inhibitor