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Proteintech
TFPT Polyclonal Antibody
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Product Details
10097-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TFPT Fusion Protein Ag0131 (39-253 aa encoded by BC001728)
Conjugate
Form
Liquid
Concentration
0.42 mg/mL
Amount
63 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SELETEVEF VSGGLGGSGL RERDEEEEAA RGRRRRQREL NRRKYQALGR RCREIEQVNE RVLNRLHQVQ RITRRLQQER RFLMRVLDSY GDDYRASQFT IVLEDEGSQG TDAPTPGNAE NEPPEKETLS PPRRTPAPPE PGSPAPGEGP SGRKRRRVPR DGRRAGNALT PELAPVQIKV EEDFGFEADE ALDSSWVSRG PDKLLPYPTL ASPAS (39-253 aa encoded by B C001728)
Target Information
TFPT component of the chromatin-remodeling INO80 complex which, in addition to chromatin remodeling implicated in crucial functions such as DNA repair, checkpoint regulation, DNA replication, telomemere maintenance and chromosome segregation. This protein appears to promote apoptosis in a TP53/p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: amida, partner of the E2A; INO80 complex subunit F; Protein amida; Protein FB1; TCF3 (E2A) fusion partner (in childhood Leukemia); TCF3 fusion partner; TCF3 fusion partner homolog
Gene Aliases: 2400004F01Rik; AI450389; Amida; FB1; INO80F; TFPT
UniProt ID: (Human) P0C1Z6, (Rat) Q9JMG6, (Mouse) Q3U1J1
Entrez Gene ID: (Human) 29844, (Rat) 85423, (Mouse) 69714
telomere maintenance
regulation of DNA replication
DNA repair
regulation of DNA repair
DNA recombination
chromatin remodeling
apoptotic process
cellular response to DNA damage stimulus
regulation of chromosome organization
positive regulation of apoptotic process
positive regulation of DNA repair
positive regulation of transcription, DNA-templated
regulation of embryonic development
regulation of cell cycle
regulation of DNA strand elongation
apoptotic signaling pathway
positive regulation of telomere maintenance in response to DNA damage
transcription, DNA-templated
regulation of transcription, DNA-templated
male gonad development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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