Immunogen sequence: SLSTCSTLDM DQFMRKRIEA IRGQILSKLK LTSPPEDYPE PEEVPPEVIS IYNSTRDLLQ EKASRRAAAC ERERSDEEYY AKEVYKIDMP PFFPSETVCP VVTTPSGSVG SLCSRQSQVL CGYLDAIPPT FYRPYFRIVR F; Positive Samples: A-549, Mouse heart
TGF betas mediate many cell-cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.
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Protein Aliases: BSC-1 cell growth inhibitor; Cetermin; G-TSF; Glioblastoma-derived T-cell suppressor factor; LAP; Latency-associated peptide; polyergin; prepro-transforming growth factor beta-2; TGF beta 2 protein; TGF-beta-2; Transforming growth factor beta-2; Transforming growth factor beta-2 proprotein; transforming growth factor, beta 2
Gene Aliases: BB105277; LDS4; TGF-B2; TGF-beta2; Tgfb-2; TGFB2