This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: MMDGPRSDVG RWGGNPLQPP TTPSPEPEPE PDGRSRRGGG RSFWARCCGC CSCRNAADDD WGPEPSDSRG RGSSSGTRRP GSRGSDSRRP VSRGSGVNAA
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).
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Protein Aliases: Epidermal TGase; ICR2; K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase; KTG; LI; LI1; Protein-glutamine gamma-glutamyltransferase K; protein-glutamine-gamma-glutamyltransferase); TG(K); TGASE; TGase K; TGase-1; TGK; Transglutaminase 1 (K polypeptide epidermal type I; transglutaminase 1 isoform; Transglutaminase K; transglutaminase, keratinocyte; Transglutaminase-1
Gene Aliases: ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK; TGM1
UniProt ID: (Human) P22735
Entrez Gene ID: (Human) 7051