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      TGN46 Polyclonal Antibody

      See 1 other TGN46 antibodies ›
      TGN46 Polyclonal Antibody for Western Blot, IF, ICC, IHC and IHC (P)

      Catalog#: PA5-23068 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-23068 100 µL
      349.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

      Anti-Rabbit Secondary Antibodies (264)
      Alexa Fluor® Anti-Rabbit Secondary Antibodies (69)
      HRP Anti-Rabbit Secondary Antibodies (30)

      Product Details

      References

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Published species reactivity Human
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen A synthetic peptide made to an internal region of the human TGOLN2 protein (within residues 200-350).
      Conjugate Unconjugated
      Form Liquid
      Concentration 0.66 mg/ml
      Purification Antigen affinity chromatography
      Storage buffer PBS with 30% glycerol
      Contains 0.05% sodium azide
      Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
      Tested Applications Dilution *
      Immunocytochemistry (ICC) 1:500
      Immunofluorescence (IF) 1:500
      Immunohistochemistry (IHC) 1:400
      Immunohistochemistry (Paraffin) (IHC (P)) 1:400
      Western Blot (WB) 1:100-1:2000

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Published Applications
      Miscellaneous PubMed (MISC) See 1 publications below

      Product Specific Information

      Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

      Background/Target Information

      The TGOLN2 protein may be involved in regulating membrane traffic to and from the trans-Golgi network. There are several isoforms, which are produced by alternative splicing. The upregulation of TGOLN2 has been indicated in association with suicide cases. However, protein analysis has not verified that there is any direct correlation between suicide and TGOLN2 without alcohol influence. It is a highly glycosylated protein.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      References

      Miscellaneous PubMed

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Human Not Cited Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry.
      PA5-23068 was used in immunocytochemistry to map the topography of the human papillomavirus L2 protein during infection       		DiGiuseppe S,Keiffer TR,Bienkowska-Haba M,Luszczek W,Guion LG,Müller M,Sapp M Journal of virology (89:10442) 2015

      Bioinformatics

      Protein Aliases:

      48; 51kD isoforms); TGN38; TGN38 homolog; TGN46; TGN48; TGN51; Trans-Golgi network integral membrane protein 2; trans-Golgi network protein (46; trans-Golgi network protein (46, 48, 51kD isoforms); Trans-Golgi network protein TGN51; TTGN2

      Gene Aliases:

      TGN38; TGN46; TGN48; TGN51; TGOLN2; TTGN2

      UniProt ID:

      (Human) O43493

      Entrez Gene ID:

      (Human) 10618

      Molecular Function:

      membrane traffic protein

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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