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Immunogen sequence: VCQSSPCEAE ELRYSLHVGP WSTCSMPHSR QVRQARRRGK NKEREKDRSK GVKDPEAREL IKKKRNRNRQ NRQENKYWDI QIGYQTREVM CINKTGKAAD LSFCQQEKLP MTFQSC
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 86%.
The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. [provided by RefSeq, Aug 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Thrombospondin type-1 domain-containing protein 7A; thrombospondin, type I, domain containing 7A
Gene Aliases: KIAA0960; THSD7A
UniProt ID: (Human) Q9UPZ6
Entrez Gene ID: (Human) 221981
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