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Immunogen sequence: MEGGFGSDFG GSGSGKLDPG LIMEQVKVQI AVANAQELLQ RMTDKCFRKC IGKPGGSLDN SEQKCIAMCM DRYMD
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
This gene encodes a member of the evolutionarily conserved TIMM (translocase of inner mitochondrial membrane) family of proteins that function as chaperones in the import of proteins from the cytoplasm into the mitochondrial inner membrane. Proteins of this family play a role in collecting substrate proteins from the translocase of the outer mitochondrial membrane (TOM) complex and delivering them to either the sorting and assembly machinery in the outer mitochondrial membrane (SAM) complex or the TIMM22 complex in the inner mitochondrial membrane. The encoded protein and the translocase of mitochondrial inner membrane 8a protein form a 70 kDa complex in the intermembrane space.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mitochondrial import inner membrane translocase subunit Tim13; mitochondrial import inner membrane translocase subunit Tim13B; translocase of inner mitochondrial membrane 13 homolog
Gene Aliases: ppv1; TIM13; TIM13B; TIMM13; TIMM13A; TIMM13B
UniProt ID: (Human) Q9Y5L4
Entrez Gene ID: (Human) 26517
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