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Product Details
PA5-120549
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human TIMM44 (NP_006342.2).
Conjugate
Form
Liquid
Concentration
2.22 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914121
Product Specific Information
Positive test controls include: U-87MG, K562, mouse liver, rat kidney.^M
^M
Immunogen sequence: AKTAKQSAES VSKGGEKLGR TAAFRALSQG VESVKKEIDD SVLGQTGPYR RPQRLRKRTE FAGDKFKEEK VFEPNEEALG VVLHKDSKWY QQWKDFKENN VVFNRFFEMK MKYDESDNAF IRASRALTDK VTDLLGGLFS KTEMSEVLTE ILRVDPAFDK DRFLKQCEND IIPNVLEAMI SGELDILKDW CYEATYSQLA HPIQQAKALG LQFHSRILDI DNVDLAMGKM MEQGPVLIIT FQAQLVMVVR NPKGEVVEGD PDKVLRMLYV WALCRDQDEL NPYAAWRLLD ISASSTEQIL
Target Information
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mitochondrial import inner membrane translocase subunit TIM44; translocase of inner mitochondrial membrane 44 homolog; translocator of inner mitochondrial membrane 44; translocator of inner mitochondrial membrane 44; DNA segment, Chr 8, ERATO Doi 118, expressed
Gene Aliases: 0710005E20Rik; D8Ertd118e; MIMT44; TIM44; TIMM44
UniProt ID: (Human) O43615, (Mouse) O35857, (Rat) O35094
Entrez Gene ID: (Human) 10469, (Mouse) 21856, (Rat) 29635
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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