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Proteintech
TIPIN Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
11972-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TIPIN Fusion Protein Ag2595 (1-301 aa encoded by BC000870)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLEPQENGV IDLPDYEHVE DETFPPFPPP ASPERQDGEG TEPDEESGNG APVPVPPKRT VKRNIPKLDA QRLISERGLP ALRHVFDKAK FKGKGHEAED LKMLIRHMEH WAHRLFPKLQ FEDFIDRVEY LGSKKEVQTC LKRIRLDLPI LHEDFVSNND EVAENNEHDV TSTELDPFLT NLSESEMFAS ELSRSLTEEQ QQRIERNKQL ALERRQAKLL SNSQTLGNDM LMNTPRAHTV EEVNTDEDQK EESNGLNEDI LDNPCNDAIA NTLNEEETLL DQSFKNVQQQ LDATSRNITE AR (1-301 aa encoded by BC000870)
Target Information
Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CSM3 homolog; FLJ20516; unnamed protein product
Gene Aliases: 1110005A05Rik; 1110018P21Rik; RGD1564084; UV98
UniProt ID: (Human) Q9BVW5, (Rat) Q4QR88, (Mouse) Q91WA1
Entrez Gene ID: (Human) 54962, (Rat) 363076, (Mouse) 66131
DNA replication checkpoint
DNA damage checkpoint
cellular response to DNA damage stimulus
positive regulation of cell proliferation
response to UV
replication fork processing
intra-S DNA damage checkpoint
replication fork arrest
cell cycle phase transition
regulation of nuclear cell cycle DNA replication
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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