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Product Details
PA5-98195
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Thymidine kinase, cytosolic protein (2-234AA)
Conjugate
Form
Liquid
Concentration
5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2812808
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.7.1.21; KITH; thymidine kinase 1 soluble isoform; thymidine kinase 1, soluble; Thymidine kinase, cytosolic; thymidine kinase-1
Gene Aliases: TK1; TK2
UniProt ID: (Human) P04183
Entrez Gene ID: (Human) 7083
liver development
nucleobase-containing compound metabolic process
DNA metabolic process
deoxyribonucleoside monophosphate biosynthetic process
nucleotide biosynthetic process
response to toxic substance
skeletal muscle cell proliferation
phosphorylation
response to nutrient levels
pyrimidine nucleoside salvage
thymidine metabolic process
response to copper ion
digestive tract development
protein homotetramerization
response to cortisol
fetal process involved in parturition
DNA biosynthetic process
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