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Fabgennix
TLR10 Polyclonal Antibody, FITC
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Product Details
TLR10-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chimpanzee,
Human,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 380-430 on human TLR10 protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Its exact function is not known. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD290; MGC104967; MGC126398; MGC126399; TLR10; Toll-like receptor 10; unnamed protein product
Gene Aliases: CD290; TLR10; UNQ315/PRO358
UniProt ID: (Human) Q9BXR5
Entrez Gene ID: (Chimpanzee) 461166, (Human) 81793, (Rat) 305355
toll-like receptor signaling pathway
immune system process
inflammatory response
immune response
signal transduction
innate immune response
cellular response to bacterial lipopeptide
MyD88-dependent toll-like receptor signaling pathway
toll-like receptor 10 signaling pathway
regulation of cytokine secretion
positive regulation of inflammatory response
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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