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Invitrogen
TMPRSS11D Polyclonal Antibody
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FIGURE: 1 / 2
TMPRSS11D Antibody (PA5-87660) in WB
Western blot analysis of TMPRSS11D in extracts of various cell lines. Samples were incubated with TMPRSS11D Polyclonal antibody (Product # PA5-87660) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-87660
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 42-292 of human TMPRSS11D (NP_0042531)
Conjugate
Form
Liquid
Concentration
1.24 mg/mL
Amount
124 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AFDQKSYFYR SSFQLLNVEY NSQLNSPATQ EYRTLSGRIE SLITKTFKES NLRNQFIRAH VAKLRQDGSG VRADVVMKFQ FTRNNNGASM KSRIESVLRQ MLNNSGNLEI NPSTEITSLT DQAAANWLIN ECGAGPDLIT LSEQRILGGT EAEEGSWPWQ VSLRLNNAHH CGGSLINNMW ILTAAHCFRS NSNPRDWIAT SGISTTFPKL RMRVRNILIH NNYKSATHEN DIALVRLENS VTFTKDIHSV C; Positive Samples: HepG2, Mouse liver, Mouse kidney, Mouse skeletal muscle, Rat liver, Rat kidney; Cellular Location: Cell membrane, Single-pass type II membrane protein
Target Information
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adrenal secretory serine protease; airway spesific trypsin-like protease; Airway trypsin-like protease; AsP; AT; MGC150587; MGC150588; Transmembrane protease serine 11D; transmembrane protease, serine 11D; transmembrane serine protease 11D; unnamed protein product
Gene Aliases: ASP; AST; BC020151; HAT; Mat; Rat; TMPRSS11D
UniProt ID: (Human) O60235, (Rat) Q8VHJ4, (Mouse) Q8VHK8
Entrez Gene ID: (Human) 9407, (Rat) 64565, (Mouse) 231382
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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