Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Immunogen sequence: AFDQKSYFYR SSFQLLNVEY NSQLNSPATQ EYRTLSGRIE SLITKTFKES NLRNQFIRAH VAKLRQDGSG VRADVVMKFQ FTRNNNGASM KSRIESVLRQ MLNNSGNLEI NPSTEITSLT DQAAANWLIN ECGAGPDLIT LSEQRILGGT EAEEGSWPWQ VSLRLNNAHH CGGSLINNMW ILTAAHCFRS NSNPRDWIAT SGISTTFPKL RMRVRNILIH NNYKSATHEN DIALVRLENS VTFTKDIHSV C; Positive Samples: HepG2, Mouse liver, Mouse kidney, Mouse skeletal muscle, Rat liver, Rat kidney; Cellular Location: Cell membrane, Single-pass type II membrane protein
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adrenal secretory serine protease; airway spesific trypsin-like protease; airway trypsin like protease; Airway trypsin-like protease; AsP; AT; MGC150587; MGC150588; Transmembrane protease serine 11D; transmembrane serine protease 11D
Gene Aliases: AsP; AST; BC020151; HAT; Mat; Rat; TMPRSS11D
UniProt ID: (Human) O60235, (Rat) Q8VHJ4, (Mouse) Q8VHK8
Entrez Gene ID: (Human) 9407, (Rat) 64565, (Mouse) 231382
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