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Invitrogen
TMPRSS11F Polyclonal Antibody
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Product Details
PA5-55461
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TMPRSS11F. Recombinant protein control fragment (Product #RP-90611).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NKDPTQWIAT FGATITPPAV KRNVRKIILH ENYHRETNEN DIALVQLSTG VEFSNIVQRV CLPDSSIKLP PKTSVFVTGF GSIVDDGPIQ NTLRQARVET ISTDVCNRKD VYDG
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.
Target Information
TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Airway trypsin-like protease 4; Transmembrane protease serine 11F
Gene Aliases: HATL4; TMPRSS11F
UniProt ID: (Human) Q6ZWK6
Entrez Gene ID: (Human) 389208
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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