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Proteintech
TMPRSS5 Polyclonal Antibody
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Product Details
24616-1-AP
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TMPRSS5 Fusion Protein Ag18493 (109-457 aa encoded by BC121803)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TVSFRINSE DFLLEAQVRD QPRWLLVCHE GWSPALGLQI CWSLGHLRLT HHKGVNLTDI KLNSSQEFAQ LSPRLGGFLE EAWQPRNNCT SGQVVSLRCS ECGARPLASR IVGGQSVAPG RWPWQASVAL GFRHTCGGSV LAPRWVVTAA HCMHSFRLAR LSSWRVHAGL VSHSAVRPHQ GALVERIIPH PLYSAQNHDY DVALLRLQTA LNFSDTVGAV CLPAKEQHFP KGSRCWVSGW GHTHPSHTYS SDMLQDTVVP LLSTQLCNSS CVYSGALTPR MLCAGYLDGR ADACQGDSGG PLVCPDGDTW RLVGVVSWGR GCAEPNHPGV YAKVAEFLDW IHDTAQDSLL (109-457 aa encoded by BC121803)
Target Information
Spinesin, also known as Serine protease 22 (PRSS22), is a gene located on chromosome 16p11.2 that encodes a trypsin-like serine protease predominantly expressed in the brain and airway tissues. This protease is part of the large family of serine proteases, characterized by their involvement in a variety of physiological processes, including digestion, immune response, and cellular remodeling. In the nervous system, Spinesin is implicated in synaptic function and plasticity, with potential roles in modulating neural connectivity and communication. It is also involved in processing extracellular matrix components, which can influence cell adhesion and migration, contributing to tissue remodeling and repair processes. Dysregulation of Spinesin expression or activity may impact neural development and has been associated with certain neurological disorders. Research into Spinesin continues to explore its specific functions in the nervous system and its potential therapeutic applications in neurobiology and regenerative medicine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adrenal mitochondrial protease; MGC141886; MGC148044; Spinesin; Transmembrane protease serine 5; transmembrane protease, serine 5; transmembrane protease, serine 5 (spinesin); unnamed protein product
Gene Aliases: Amp; SPINESIN; TMPRSS5
UniProt ID: (Human) Q9H3S3
Entrez Gene ID: (Human) 80975, (Rat) 266681
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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