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Abnova
TMPRSS5 Polyclonal Antibody, MaxPab™
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Product Details
H00080975-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TMPRSS5 (NP_110397, 1 a.a. approximately 457 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSLMLDDQPP MEAQYAEEGP GPGIFRAEPG DQQHPISQAV CWRSMRRGCA VLGALGLLAG AGVGSWLLVL YLCPAASQPI SGTLQDEEIT LSCSEASAEE ALLPALPKTV SFRINSEDFL LEAQVRDQPR WLLVCHEGWS PALGLQICWS LGHLRLTHHK GVNLTDIKLN SSQEFAQLSP RLGGFLEEAW QPRNNCTSGQ VVSLRCSECG ARPLASRIVG GQSVAPGRWP WQASVALGFR HTCGGSVLAP RWVVTAAHCM HSFRLARLSS WRVHAGLVSH SAVRPHQGAL VERIIPHPLY SAQNHDYDVA LLRLQTALNF SDTVGAVCLP AKEQHFPKGS RCWVSGWGHT HPSHTYSSDM LQDTVVPLFS TQLCNSSCVY SGALTPRMLC AGYLDGRADA CQGDSGGPLV CPDGDTWRLV GVVSWGRGCA EPNHPGVYAK VAEFLDWIHD TAQDSLL
Target Information
Spinesin, also known as Serine protease 22 (PRSS22), is a gene located on chromosome 16p11.2 that encodes a trypsin-like serine protease predominantly expressed in the brain and airway tissues. This protease is part of the large family of serine proteases, characterized by their involvement in a variety of physiological processes, including digestion, immune response, and cellular remodeling. In the nervous system, Spinesin is implicated in synaptic function and plasticity, with potential roles in modulating neural connectivity and communication. It is also involved in processing extracellular matrix components, which can influence cell adhesion and migration, contributing to tissue remodeling and repair processes. Dysregulation of Spinesin expression or activity may impact neural development and has been associated with certain neurological disorders. Research into Spinesin continues to explore its specific functions in the nervous system and its potential therapeutic applications in neurobiology and regenerative medicine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC141886; MGC148044; Spinesin; Transmembrane protease serine 5
Gene Aliases: SPINESIN; TMPRSS5
UniProt ID: (Human) Q9H3S3
Entrez Gene ID: (Human) 80975
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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