|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Purified recombinant human HVEM extracellular domain, expressed in NSO cells.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||0.5-1 µg/ml|
|Western Blot (WB)||0.1-0.2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30175 detects TNFRSF14 from human samples.
PA1-30175 has been successfully used in Western blot applications.
The PA1-30175 immunogen is: Purified recombinant human HVEM extracellular domain, expressed in NSO cells.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.