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Immunogen sequence: MTDQQAEAR SYLSEEMIAE FKAAFDMFDA DGGGDISVKE LGTVMRMLGQ TPTKEELDAI IEEVDEDGSG TIDFEEFLVM MVRQMKEDAK GKSEEELAEC FRIFDRNADG YIDPEELAEI FRASGEHVTD EEIESLMKDG DKNNDGRIDF DEFLKMMEGV Q (1-160 aa encoded by BC005323)
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
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Protein Aliases: skeletal troponin C; STNC; troponin C type 2 (fast); troponin C, fast skeletal; Troponin C, skeletal muscle; troponin C2, fast
Gene Aliases: Tncs; TNNC2
UniProt ID: (Human) P02585, (Mouse) P20801
Entrez Gene ID: (Human) 7125, (Rat) 296369, (Mouse) 21925
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