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Invitrogen
TNRC6A Polyclonal Antibody
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Product Details
PA5-120969
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide
Conjugate
Form
Liquid
Concentration
0.57 mg/mL
Amount
57 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: Mouse brain, Rat brain. The target is usually found in the following locations: Cytoplasm, P-body.
Immunogen sequence: QDIVGSWGIP PATGKPPGTG WLGGPIPAPA KEEEPTGWEE PSPESIRRKM EIDDGTSAWG DPSKYNYKNV NMWNKNVPNG NSRSDQQAQV HQLLTPASAI S
Target Information
TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAG repeat protein 26; CTD-2540M10.1; cytoplasmic domain GWB RNA binding protein; DKFZp666E117; EDIE; EMSY interactor protein; FLJ22043; Glycine-tryptophan protein of 182 kDa; GW182 autoantigen; MGC75384; Protein GW1; trinucleotide repeat containing 6; trinucleotide repeat containing 6A; Trinucleotide repeat-containing gene 6A protein; unnamed protein product
Gene Aliases: 2010321I05Rik; 3110054G10Rik; AW557223; CAGH26; D130023A07Rik; FAME6; GW1; GW182; KIAA1460; TNRC6; TNRC6A
UniProt ID: (Human) Q8NDV7, (Mouse) Q3UHK8
Entrez Gene ID: (Human) 27327, (Rat) 308971, (Mouse) 233833
regulation of translation
endoderm development
cellular response to starvation
gene silencing by RNA
cytoplasmic mRNA processing body assembly
gene silencing by miRNA
miRNA mediated inhibition of translation
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
biological_process
maintenance of protein location in cell
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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