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Product Details
PA5-20445
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 15 amino acid peptide near the amino terminus of the human TOCA-1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11156020
Product Specific Information
A suggested positive control is human brain tissue lysate.
PA5-20445 can be used with blocking peptide PEP-0562.
Target Information
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cdc42 effector; formin binding protein 1-like; Formin-binding protein 1-like; Toca-1; transducer of Cdc42-dependent actin assembly 1; Transducer of Cdc42-dependent actin assembly protein 1
Gene Aliases: 2610318I01Rik; AW548221; C1orf39; FNBP1L; RGD1305386; Toca-1; TOCA1
UniProt ID: (Human) Q5T0N5, (Rat) Q2HWF0
Entrez Gene ID: (Human) 54874, (Rat) 310839, (Mouse) 214459
membrane budding
autophagy
membrane invagination
vesicle organization
vesicle transport along actin filament
cilium assembly
positive regulation of GTPase activity
positive regulation of filopodium assembly
clathrin-mediated endocytosis
membrane tubulation
cell-cell adhesion
endocytosis
nervous system development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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