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Proteintech
TP53INP1 Polyclonal Antibody
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Product Details
17872-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TP53INP1 Fusion Protein Ag12358 (1-240 aa encoded by BC074868)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MFQRLNKMF VGEVSSSSNQ EPEFNEKEDD EWILVDFIDT CTGFSAEEEE EEEDISEESP TEHPSVFSCL PASLECLADT SDSCFLQFES CPMEESWFIT PPPCFTAGGL TTIKVETSPM ENLLIEHPSM SVYAVHNSCP GLSEATRGTD ELHSPSSPRV EAQNEMGQHI HCYVAALAAH TTFLEQPKSF RPSQWIKEHS ERQPLNRNSL RRQNLTRDCH PRQVKHNGWV VHQPCPRQYN Y (1-240 aa encoded by BC074868)
Target Information
A novel p53 inducible gene was identified and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: p53-dependent damage-inducible nuclear protein 1; p53-inducible p53DINP1; p53DINP1; stress induced protein; Stress-induced protein; TEAP; thymus expressed acidic protein; Thymus-expressed acidic protein; transformation related protein 53 inducible nuclear protein 1; Tumor protein p53-inducible nuclear protein 1; unnamed protein product
Gene Aliases: 2700057G22Rik; P53DINP1; SIP; SIP18; SIP27; Stinp; Teap; TP53DINP1; TP53INP1; TP53INP1A; TP53INP1B; Trp53inp1
UniProt ID: (Human) Q96A56, (Rat) Q80YE2, (Mouse) Q9QXE4
Entrez Gene ID: (Human) 94241, (Rat) 297822, (Mouse) 60599
autophagosome assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
autophagy
apoptotic process
cell cycle arrest
negative regulation of cell proliferation
response to heat
regulation of autophagy
positive regulation of autophagy
negative regulation of cell migration
cellular response to UV
positive regulation of apoptotic process
positive regulation of transcription, DNA-templated
autophagic cell death
cellular response to ethanol
cellular response to hydroperoxide
cellular response to methyl methanesulfonate
positive regulation of apoptotic signaling pathway
positive regulation of gene expression
negative regulation of gene expression
negative regulation of fibroblast proliferation
regulation of cell cycle
cellular oxidant detoxification
negative regulation of myofibroblast differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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