The antibody detects endogenous levels of total TPST1 protein.
The tyrosylprotein sulfotransferases TPST-1 and TPST-2 catalyze the sulfation of tyrosine residues within secreted and membrane-bound proteins, such as cell adhesion molecules, G-protein-coupled receptors, coagulation factors, serpins, extracellular matrix proteins, and hormones. Although both TPST-1 and TPST-2 utilize 3'-phosphoadenosine 5'-phosphosulfate as their sulfate donor, they differ in their substrate specificity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein-tyrosine sulfotransferase 1; TPST-1; transport and golgi organization 13 homolog A; Tyrosylprotein sulfotransferase 1; tyrosylprotein sulfotransferase-1
Gene Aliases: TANGO13A; TPST1
UniProt ID: (Human) O60507
Entrez Gene ID: (Human) 8460
Molecular Function: transferase