Immunogen sequence: EERSQPVKLE STRTTVRTGL DLKANKTFAY HKDMPLIFIG G
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.
The tyrosylprotein sulfotransferases TPST-1 and TPST-2 catalyze the sulfation of tyrosine residues within secreted and membrane-bound proteins, such as cell adhesion molecules, G-protein-coupled receptors, coagulation factors, serpins, extracellular matrix proteins, and hormones. Although both TPST-1 and TPST-2 utilize 3'-phosphoadenosine 5'-phosphosulfate as their sulfate donor, they differ in their substrate specificity. .
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Protein Aliases: Protein-tyrosine sulfotransferase 1; TANGO13A; TPST-1; transport and golgi organization 13 homolog A; Tyrosylprotein sulfotransferase 1; tyrosylprotein sulfotransferase-1
Gene Aliases: TANGO13A; TPST1
UniProt ID: (Human) O60507
Entrez Gene ID: (Human) 8460
Molecular Function: transferase