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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 174 and 358 of Human TRIB3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29887 targets TRIB3 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29887 immunogen is recombinant fragment corresponding to a region within amino acids 174 and 358 of Human TRIB3.
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C20orf97; neuronal cell death inducible putative kinase; neuronal cell death-inducible putative kinase; NIPK; p65-interacting inhibitor of NF-kappa-B; p65-interacting inhibitor of NF-kappaB; SKIP3; TRB-3; TRB3; tribbles homolog 3
C20orf97; NIPK; SINK; SKIP3; TRB3; TRIB3