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Product Details
H00008848-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TSC22D1 (NP_006013.1, 1 a.a. approximately 144 a.a) full-length human protein.
Conjugate
Unconjugated
Form
Liquid
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKSQWCRPVA MDLGVYQLRH FSISFLSSLL GTENASVRLD NSSSGASVVA IDNKIEQAMD LVKSHLMYAV REEVEVLKEQ IKELIEKNSQ LEQENNLLKT LASPEQLAQF QAQLQTGSPP ATTQPQGTTQ PPAQPASQGS GPTA
Target Information
TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cerebral protein 2; HUCEP-2; Regulatory protein TSC-22; RP11-269C23.2; TGFB-stimulated clone 22 homolog; TGFbeta-stimulated clone 22; transcriptional regulator TSC-22; Transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TSC22 domain family protein 1; TSC22 domain family, member 1
Gene Aliases: hucep-2; KIAA1994; Ptg-2; TGFB1I4; TSC22; TSC22D1
UniProt ID: (Human) Q15714
Entrez Gene ID: (Human) 8848
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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