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TSC22D1 Antibody (PA5-116080) in IHC (P)
Immunohistochemistry analysis of TSC22D1 in human kidney cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-116080) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-116080
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TSC22D1(Accession Q15714), corresponding to amino acid residues P1033-A1073.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900714
Product Specific Information
Antibody detects endogenous levels of total TSC22D1.
Target Information
TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cerebral protein 2; HUCEP-2; Regulatory protein TSC-22; regulatory protein Tsc22; RP11-269C23.2; TGFB-stimulated clone 22 homolog; TGFbeta-stimulated clone 22; transcriptional regulator TSC-22; transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta stimulated clone 22; Transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TSC22 domain family protein 1; TSC22 domain family, member 1; TSC22-related inducible leucine zipper 1b
Gene Aliases: AA589566; AW105905; Egr5; hucep-2; KIAA1994; Ptg-2; TGFB1I4; Tilz1b; TS22A; Tsc; TSC-22; TSC22; TSC22D1
UniProt ID: (Human) Q15714, (Mouse) P62500, (Rat) P62501
Entrez Gene ID: (Human) 8848, (Mouse) 21807, (Rat) 498545
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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