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Invitrogen
Tenascin R Polyclonal Antibody
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FIGURE: 1 / 2
Tenascin R Antibody (PA5-31143) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Tenascin R was performed in DIV9 rat E18 primary hippocampal neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Tenascin R Polyclonal Antibody (Product # PA5 31143) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-31143
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human TNR. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (91%), Rat (88%), Rhesus Monkey (98%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion; MIM 187380), TNX (TNXB; MIM 600985), and TNR (Erickson, 1993). The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Janusin; Neural recognition molecule J1-160/180; Restrictin; tenascin R (restrictin, janusin); Tenascin-R; Tenascin-R (Restrictin janusin J1-160/180); Tenascin-R (Restrictin, janusin, J1-160/180); TN-R
Gene Aliases: J1-tenascin; J1NRM; janusin; restrictin; TN-R; TNR
UniProt ID: (Human) Q92752, (Mouse) Q8BYI9, (Rat) Q05546
Entrez Gene ID: (Human) 7143, (Mouse) 21960, (Rat) 25567
cell adhesion
neuron cell-cell adhesion
axon guidance
associative learning
telencephalon cell migration
negative regulation of cell-cell adhesion
extracellular matrix organization
locomotory exploration behavior
negative regulation of axon extension involved in regeneration
negative regulation of synaptic transmission
synapse organization
neuromuscular process controlling balance
positive regulation of synaptic transmission, glutamatergic
positive regulation of transmission of nerve impulse
long-term synaptic potentiation
negative regulation of cell adhesion
negative regulation of neuron projection development
negative regulation of axon extension
modulation of synaptic transmission
nervous system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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