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Invitrogen
ThPOK Polyclonal Antibody
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Product Details
PA5-29461
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ThPok. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, HeLa, HepG2.
Predicted reactivity: Mouse (87%), Rat (87%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686G01254; hcKrox; Krueppel-related zinc finger protein cKrox; RP11-307C12.9; T-helper-inducing POZ/Krueppel-like factor; unnamed protein product; Zfp-67; zinc finger and BTB domain containing 15; Zinc finger and BTB domain-containing protein 15; Zinc finger and BTB domain-containing protein 7B; Zinc finger protein 67 homolog; Zinc finger protein 857B; Zinc finger protein Th-POK; zinc-finger transcription factor
Gene Aliases: c-KROX; CKROX; hcKROX; THPOK; vGAF; ZBTB15; ZBTB7B; ZFP-67; ZFP67; ZNF857B
UniProt ID: (Human) O15156
Entrez Gene ID: (Human) 51043
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
identical protein binding
protein homodimerization activity
histone deacetylase binding
metal ion binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
NK T cell differentiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
ectoderm development
lactation
regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression
cell differentiation
positive regulation of interleukin-17 production
response to insulin
positive regulation of CD4-positive, alpha-beta T cell differentiation
regulation of CD8-positive, alpha-beta T cell differentiation
negative regulation of CD8-positive, alpha-beta T cell differentiation
regulation of T-helper cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of insulin receptor signaling pathway
negative regulation of NK T cell proliferation
positive regulation of brown fat cell differentiation
positive regulation of cold-induced thermogenesis
adaptive thermogenesis
negative regulation of T-helper 17 cell differentiation
positive regulation of SREBP signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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