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Proteintech
Transferrin Polyclonal Antibody
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Product Details
17435-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Transferrin Fusion Protein Ag11504 (347-698 aa encoded by BC059367)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EGTCQEAPT DECKPVKWCA LSHHERLKCD EWSVNSVGKI ECVSAETTED CIAKIMNGEA DAMSLDGGFV YIAGKCGLVP VLAENYNKSD NCEDTPEAGY FAVAVVKKSA SDLTWDNLKG KKSCHTAVGR TAGWNIPMGL LYNKINHCRF DEFFSEGCAP GSKKDSSLCK LCMGSGLNLC EPNNKEGYYG YTGAFRCLVE KGDVAFVKHQ TVPQNTGGKN PDPWAKNLNE KDYELLCLDG TRKPVEEYAN CHLARAPNHA VVTRKDKEAC VHKILRQQQH LFGSNVTDCS GNFCLFRSET KDLLFRDDTV CLAKLHDRNT YEKYLGEEYV KAVGNLRKCS TSSLLEACTF RRP (347-698 aa encoded by BC059367)
Target Information
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; hypotransferrinemia with hemochromatosis; Liver regeneration-related protein LRRG03; Serotransferrin; Siderophilin; transferin; Transferrin; transferrin precursor; unnamed protein product
Gene Aliases: AI266983; Cd176; HEL-S-71p; HP; hpx; PRO1400; PRO1557; PRO2086; TF; Tfn; TFQTL1; Trf
UniProt ID: (Human) P02787, (Rat) P12346, (Mouse) Q921I1
Entrez Gene ID: (Human) 7018, (Rat) 24825, (Mouse) 22041
ion transport
iron ion transport
cellular iron ion homeostasis
cell surface receptor signaling pathway
response to bacterium
antibacterial humoral response
osteoclast differentiation
regulation of protein stability
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of receptor-mediated endocytosis
multicellular organismal iron ion homeostasis
cellular response to iron ion
ferrous iron export
response to hypoxia
retina homeostasis
apoptotic process
acute-phase response
actin filament organization
activation of JUN kinase activity
small GTPase mediated signal transduction
response to lead ion
response to organic cyclic compound
ferric iron transport
positive regulation of myelination
positive regulation of phosphorylation
positive regulation of bone resorption
positive regulation of transcription, DNA-templated
SMAD protein signal transduction
ERK1 and ERK2 cascade
positive regulation of oligodendrocyte progenitor proliferation
cellular response to cAMP
cellular response to follicle-stimulating hormone stimulus
positive regulation of cell motility
transport
iron ion transmembrane transport
iron ion homeostasis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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