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Invitrogen
UBE2E1 Polyclonal Antibody
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Product Details
PA5-72979
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide made to an N-terminal portion of the human UBCH6 protein (between residues 1-50).
Conjugate
Form
Liquid
Concentration
1.02 mg/mL
Amount
102 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 30% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
UBE2E1 catalyzes the covalent attachment of ubiquitin to other proteins. UBE2E1 mediates the selective degradation of short-lived and abnormal proteins.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (E3-independent) E2 ubiquitin-conjugating enzyme E1; E2 ubiquitin-conjugating enzyme E1; UbcH6; UbcM3; Ubiquitin carrier protein E1; ubiquitin conjugating enzyme E2E 1; ubiquitin-conjugating enzyme 5; Ubiquitin-conjugating enzyme E2 E1; ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog; Ubiquitin-protein ligase E1; unnamed protein product
Gene Aliases: Ubce5; UBCH6; ubcM2; UbcM3; UBE2E1
UniProt ID: (Human) P51965, (Mouse) P52482
Entrez Gene ID: (Human) 7324, (Mouse) 22194
protein polyubiquitination
ubiquitin-dependent protein catabolic process
protein monoubiquitination
negative regulation of gene expression
protein ubiquitination
ISG15-protein conjugation
positive regulation of transcription from RNA polymerase II promoter
protein K48-linked ubiquitination
histone monoubiquitination
histone H2B ubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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