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Proteintech
UBQLN2 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-23449
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBQLN2 fusion protein Ag20149
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAENGESSG PPRPSRGPAA AQGSAAAPAE PKIIKVTVKT PKEKEEFAVP ENSSVQQFKE AISKRFKSQT DQLVLIFAGK ILKDQDTLIQ HGIHDGLTVH LVIKSQNRPQ GQSTQPSNAA GTNTTSASTP RSNSTPISTN SNPFGLGSLG GLAGLSSLGL SSTNFSELQS QMQQQLMASP EMMIQIMENP FVQSMLSNPD LMRQLIMANP QMQQLIQRNP EISHLLNNPD IMRQTLEIAR NPAMMQEMMR NQDLALSNLE SIPGGYNALR RMYTDIQEPM LNAAQEQFGG NPFASVGSSS SSGEGTQPSR TENRDPLPNP WAPPPATQSS ATTSTTTSTG SGSGNSSSNA TGNTVAAANY VASIFSTPGM QSLLQQITEN PQLIQNMLSA PYMRSMMQSL SQNPDLAAQM MLNSPLFTAN PQLQEQMRPQ LPAFLQQMQN PDTLSAMSNP RAMQALMQIQ QGLQTLATEA PGLIPSFTPG VGVGVLGTAI GPVGPVTPIG PIGPIVPFTP IGPIGPIGPT GPAAPPGSTG SGGPTGPTVS SAAPSETTSP TSESGPNQQF IQQMVQALAG ANAPQLPNPE VRFQQQLEQL NAMGFLNREA NLQALIATGG DINAAIERLL GSQPS
Target Information
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chap1; DSK2 homolog; HRIHFB2157; Nedd4 binding protein 4; PLIC-2; Protein linking IAP with cytoskeleton 2; Ubiquilin-2; Ubiquitin-like product Chap1/Dsk2; ubiquitin-like type II; unnamed protein product
Gene Aliases: ALS15; CHAP1; DSK2; HRIHFB2157; N4BP4; PLIC2; RGD1563566; UBQLN2
UniProt ID: (Human) Q9UHD9
Entrez Gene ID: (Human) 29978, (Rat) 317396
autophagosome assembly
ubiquitin-dependent protein catabolic process
autophagy
regulation of macroautophagy
ERAD pathway
negative regulation of transport
negative regulation of clathrin-mediated endocytosis
negative regulation of G-protein coupled receptor internalization
positive regulation of ERAD pathway
regulation of autophagosome assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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