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Product Details
PA5-84520
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UBXN6. Recombinant protein control fragment (Product #RP-105214).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791671
Product Specific Information
Immunogen sequence: KFFQEFKADI KFKSAGPGQK LKESVGEKAH KEKPNQPAPR PPRQGPTNEA QMAAAAALAR LEQKQSRA
Target Information
May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes (PubMed:26475856). As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation (PubMed:21822278, PubMed:23335559). It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (PubMed:19275885). Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTB-50L17.16; UBX domain containing 1; UBX domain-containing 1; UBX domain-containing 2; UBX domain-containing protein 1; UBX domain-containing protein 6
Gene Aliases: UBXD1; UBXDC2; UBXN6
UniProt ID: (Human) Q9BZV1
Entrez Gene ID: (Human) 80700
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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