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Product Details
PA5-76748
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant full length Human UROD. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2720475 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: UPD; URO D; Uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase
Gene Aliases: AI323803; PCT; UPD; Uro-d; UROD
UniProt ID: (Human) P06132, (Mouse) P70697
Entrez Gene ID: (Human) 7389, (Mouse) 22275
Molecular Function:
methyltransferase
liver development
protoporphyrinogen IX biosynthetic process
heme biosynthetic process
response to iron ion
response to amine
response to estradiol
response to ethanol
uroporphyrinogen III metabolic process
response to mercury ion
response to methylmercury
response to fungicide
cellular response to arsenic-containing substance
porphyrin-containing compound biosynthetic process
heme metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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