|Immunohistochemistry (Paraffin) (IHC (P))||Assay-dependent|
|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Bovine, Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||synthetic peptide DRKVAREFRHKVD, corresponding to N terminal amino acids 2-14 of Human USH1C.|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-31347 detects USH1C from human samples.
PA1-31347 has been successfully used in Western blot applications.
The PA1-31347 immunogen is: Synthetic peptide: DRKVAREFRHKVD, corresponding to N terminal amino acids 2-14 of Human USH1C.
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AIE-75; Antigen NY-CO-38/NY-CO-37; Autoimmune enteropathy-related antigen AIE-75; DFNB18; Harmonin; harmonin a1; NY-CO-37; NY-CO-38; PDZ domain-containing protein; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; Protein PDZ-73; Renal carcinoma antigen NY-REN-3; ush1cpst; Usher syndrome 1C (autosomal recessive, severe); Usher syndrome 1C homolog; Usher syndrome type-1C protein; Usher syndrome type-1C protein homolog
Gene Aliases: 2010016F01Rik; AIE-75; AIE75; BOS_14475; DFNB18; DFNB18A; harmonin; NY-CO-37; NY-CO-38; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; PDZD7C; USH1C; ush1cpst
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