Synaptobrevins/VAMPs, syntaxins, and the 25-kDa synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CEB; Cellubrevin; Synaptobrevin-3; vamp; VAMP-3; Vesicle-associated membrane protein 3
Gene Aliases: CEB; D130027G05Rik; SYB3; VAMP-3; VAMP3