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Bioss
VASH1 Polyclonal Antibody
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Product Details
BS-1505R
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human VASH1, amino acids 281-365.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
VASH1 is a protein that possesses actin binding activity and metallocarboxypeptidase activity. It is involved in several processes including negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, and proteolysis. VASH1 acts upstream of or within processes such as negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, and negative regulation of lymphangiogenesis. It is located in the apical part of the cell, endoplasmic reticulum, and extracellular space. VASH1 is implicated in liver cirrhosis and portal hypertension, and is a biomarker of liver cirrhosis. Diseases associated with VASH1 include Portal Hypertension and Myasthenic Syndrome, Congenital, 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TTCP 1; Tubulin carboxypeptidase 1; Tubulinyl-Tyr carboxypeptidase 1; Tyrosine carboxypeptidase 1; vasohibin 1; Vasohibin-1
Gene Aliases: AI834978; D930046M13Rik; G630009D10Rik; KIAA1036; RGD1564082; VASH; VASH1
UniProt ID: (Human) Q7L8A9, (Mouse) Q8C1W1
Entrez Gene ID: (Human) 22846, (Mouse) 238328, (Rat) 503052
angiogenesis
negative regulation of endothelial cell proliferation
cell cycle arrest
response to wounding
negative regulation of endothelial cell migration
negative regulation of angiogenesis
negative regulation of blood vessel endothelial cell migration
negative regulation of lymphangiogenesis
regulation of cellular senescence
cell cycle
positive regulation of gene expression
regulation of angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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