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Proteintech
VCPIP1 Polyclonal Antibody
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Product Details
17802-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VCPIP1 Fusion Protein Ag12035 (1-352 aa encoded by BC094799)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Amount
67.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSQPPPPPP PLPPPPPPPE APQTPSSLAS AAASGGLLKR RDRRILSGSC PDPKCQARLF FPASGSVSIE CTECGQRHEQ QQLLGVEEVT DPDVVLHNLL RNALLGVTGA PKKNTELVKV MGLSNYHCKL LSPILARYGM DKQTGRAKLL RDMNQGELFD CALLGDRAFL IEPEHVNTVG YGKDRSGSLL YLHDTLEDIK RANKSQECLI PVHVDGDGHC LVHAVSRALV GRELFWHALR ENLKQHFQQH LARYQALFHD FIDAAEWEDI INECDPLFVP PEGVPLGLRN IHIFGLANVL HRPIILLDSL SGMRSSGDYS ATFLPGLIPA EKCTGKDGHL NKPICIAWSS SGR (1-352 aa encoded by BC094799)
Target Information
Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deubiquitinating protein VCIP135; Deubiquitinating protein VCPIP1; unnamed protein product; Valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCP/p47 complex-interacting 135-kDa protein
Gene Aliases: 4932442A08; 5730421J18Rik; 5730538E15Rik; DUBA3; KIAA1850; mKIAA1850; VCIP135; VCPIP1
UniProt ID: (Human) Q96JH7, (Mouse) Q8CDG3
Entrez Gene ID: (Human) 80124, (Mouse) 70675
DNA repair
proteolysis
cellular response to DNA damage stimulus
Golgi organization
endoplasmic reticulum membrane fusion
protein ubiquitination
protein deubiquitination
protein K11-linked deubiquitination
protein K48-linked deubiquitination
Golgi reassembly
protein-DNA covalent cross-linking repair
regulation of protein localization to chromatin
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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