|Tested species reactivity||Bovine, Human, Mouse, Rabbit, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Chicken / IgY|
|Storage buffer||1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA1-958 detects VDAC2 in mouse, rat, human, rabbit, and bovine samples.
PA1-958 has been used successfully in Western blot procedures. By Western blot PA1-958 is specific for the ~30 kDa VDAC2 protein.
The PA1-958 immunogen corresponds to chicken recombinant VDAC2 protein.
The Voltage-Dependant Anion Channel (VDAC) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC2 appears to be only expressed in the heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Reactive oxygen species and permeability transition pore in rat liver and kidney mitoplasts.
PA1-958 was used in western blot to investigate the characteristics of permeability transition pore in intact mitochondria and mitoplasts
|Ronchi JA,Vercesi AE,Castilho RF||Journal of bioenergetics and biomembranes (43:709)||2011|