Product References
Platinum Chemotherapy Induces Lymphangiogenesis in Cancerous and Healthy Tissues That Can be Prevented With Adjuvant Anti-VEGFR3 Therapy.
Frontiers in oncology
Harris AR,Esparza S,Azimi MS,Cornelison R,Azar FN,Llaneza DC,Belanger M,Mathew A,Tkachenko S,Perez MJ,Rosean CB,Bostic RR,Cornelison RC,Tate KM,Peirce-Cottler SM,Paquette C,Mills A,Landen CN,Saucerman J,Dillon PM,Pompano RR,Rutkowski MA,Munson JM
16-5988-85 was used in In vivo experiments to show that carboplatin treatment of healthy mice prior to mammary tumor inoculation increased cancer metastasis as compared to no pre-treatment and that these platinum-induced phenomena could be blocked by VEGFR3 inhibition.
Mon Nov 21 00:00:00 EST 2022
VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome.
Life science alliance
Cioffi S,Flore G,Martucciello S,Bilio M,Turturo MG,Illingworth E
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Mon Oct 10 00:00:00 EDT 2022
Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
Nature communications
Meçe O,Houbaert D,Sassano ML,Durré T,Maes H,Schaaf M,More S,Ganne M,García-Caballero M,Borri M,Verhoeven J,Agrawal M,Jacobs K,Bergers G,Blacher S,Ghesquière B,Dewerchin M,Swinnen JV,Vinckier S,Soengas MS,Carmeliet P,Noël A,Agostinis P
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Thu May 19 00:00:00 EDT 2022
Endothelial cells in the innate response to allergens and initiation of atopic asthma.
The Journal of clinical investigation
Asosingh K,Weiss K,Queisser K,Wanner N,Yin M,Aronica M,Erzurum S
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Mon Jul 02 00:00:00 EDT 2018
G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling.
Cell reports
Majumder S,Zhu G,Xu X,Senchanthisai S,Jiang D,Liu H,Xue C,Wang X,Coia H,Cui Z,Smolock EM,Libby RT,Berk BC,Pang J
16-5988 was used in Western Blotting to show that GIT1 inhibits the Notch1-Dll4 signaling pathway by competing with Notch1 ANK domain for binding to RBP-J in stalk cells.
Tue Dec 06 00:00:00 EST 2016
G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling.
Cell reports
Majumder S,Zhu G,Xu X,Senchanthisai S,Jiang D,Liu H,Xue C,Wang X,Coia H,Cui Z,Smolock EM,Libby RT,Berk BC,Pang J
16-5988 was used in Western Blotting to show that GIT1 inhibits the Notch1-Dll4 signaling pathway by competing with Notch1 ANK domain for binding to RBP-J in stalk cells.
Tue Dec 06 00:00:00 EST 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury.
The Journal of pathology
Sato T,Paquet-Fifield S,Harris NC,Roufail S,Turner DJ,Yuan Y,Zhang YF,Fox SB,Hibbs ML,Wilkinson-Berka JL,Williams RA,Stacker SA,Sly PD,Achen MG
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Wed Jun 01 00:00:00 EDT 2016
A Selenium Containing Inhibitor for the Treatment of Hepatocellular Cancer.
Pharmaceuticals (Basel, Switzerland)
Tagaram HR,Desai D,Li G,Liu D,Rountree CB,Gowda K,Berg A,Amin S,Staveley-O'Carroll KF,Kimchi ET
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Thu Mar 24 00:00:00 EDT 2016
A Selenium Containing Inhibitor for the Treatment of Hepatocellular Cancer.
Pharmaceuticals (Basel, Switzerland)
Tagaram HR,Desai D,Li G,Liu D,Rountree CB,Gowda K,Berg A,Amin S,Staveley-O'Carroll KF,Kimchi ET
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Thu Mar 24 00:00:00 EDT 2016
Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics.
Transplantation
Iwami D,Brinkman CC,Bromberg JS
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics.
Transplantation
Iwami D,Brinkman CC,Bromberg JS
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
PloS one
Izumi N,Helker C,Ehling M,Behrens A,Herzog W,Adams RH
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunofluorescence
Tue Apr 02 00:00:00 EDT 2013
Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
PloS one
Izumi N,Helker C,Ehling M,Behrens A,Herzog W,Adams RH
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunofluorescence
Tue Apr 02 00:00:00 EDT 2013
Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
Cell death and differentiation
Cesca F,Yabe A,Spencer-Dene B,Scholz-Starke J,Medrihan L,Maden CH,Gerhardt H,Orriss IR,Baldelli P,Al-Qatari M,Koltzenburg M,Adams RH,Benfenati F,Schiavo G
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Western Blot
Wed Feb 01 00:00:00 EST 2012
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature.
BMC developmental biology
Kim H,Nguyen VP,Petrova TV,Cruz M,Alitalo K,Dumont DJ
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Mon Jun 28 00:00:00 EDT 2010
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature.
BMC developmental biology
Kim H,Nguyen VP,Petrova TV,Cruz M,Alitalo K,Dumont DJ
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Mon Jun 28 00:00:00 EDT 2010
Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signaling.
Molecular and cellular biology
Taniguchi K,Kohno R,Ayada T,Kato R,Ichiyama K,Morisada T,Oike Y,Yonemitsu Y,Maehara Y,Yoshimura A
16-5988 was used in Western Blotting to investigate the overlap in functions of Spred-1 and Spred-2, showing that they are essential for embryonic lymphangiogenesis by regulating VEGFR3 signalling.
Fri Jun 01 00:00:00 EDT 2007
Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signaling.
Molecular and cellular biology
Taniguchi K,Kohno R,Ayada T,Kato R,Ichiyama K,Morisada T,Oike Y,Yonemitsu Y,Maehara Y,Yoshimura A
16-5988 was used in Western Blotting to investigate the overlap in functions of Spred-1 and Spred-2, showing that they are essential for embryonic lymphangiogenesis by regulating VEGFR3 signalling.
Fri Jun 01 00:00:00 EDT 2007
Vascular endothelial growth factor-C and its receptor VEGFR-3 in the nasal mucosa and in nasopharyngeal tumors.
The American journal of pathology
Saaristo A,Partanen TA,Arola J,Jussila L,Hytönen M,Mäkitie A,Vento S,Kaipainen A,Malmberg H,Alitalo K
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Sat Jul 01 00:00:00 EDT 2000
Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing.
The American journal of pathology
Paavonen K,Puolakkainen P,Jussila L,Jahkola T,Alitalo K
Published figure using VEGF Receptor 3 monoclonal antibody (Product # 16-5988-85) in Immunohistochemistry
Mon May 01 00:00:00 EDT 2000