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Proteintech
VGAT Polyclonal Antibody
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Product Details
14471-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Plant
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VGAT Fusion Protein Ag5843 (1-124 aa encoded by BC053582)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATLLRSKL SNVATSVSNK SQAKMSGMFA RMGFQAATDE EAVGFAHCDD LDFEHRQGLQ MDILKAEGEP CGDEGAEAPV EGDIHYQRGS GAPLPPSGSK DQVGGGGEFG GHDKPKITAW EAGWN (1-124 aa encoded by BC053582)
Target Information
The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GABA and glycine transporter; GVAT; hVIAAT; mVGAT; mVIAAT; rat UNC-47 homolog; rGVAT; RUNC-47; solute carrier family 32 (GABA vesicular transporter), member 1; Solute carrier family 32 member 1; vasicular inhibitory amino acid transporter 10D; Vesicular GABA and glycine transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter
Gene Aliases: R75019; SLC32A1; VGAT; VIAAT
UniProt ID: (Human) Q9H598, (Rat) O35458, (Mouse) O35633
Entrez Gene ID: (Human) 140679, (Rat) 83612, (Mouse) 22348
amino acid transmembrane transport
neurotransmitter transport
aging
gamma-aminobutyric acid transport
glycine transport
proton transport
sodium ion transmembrane transport
L-alpha-amino acid transmembrane transport
transport
ion transport
neurotransmitter secretion
amine transport
hippocampus development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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