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Invitrogen
VIPR1 Polyclonal Antibody
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Product Details
PA3-113
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Guinea pig,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, KLH conjugated, corresponding to the residues T(438) R V S P G A R R S S S F Q A E V S L V(457) of human VPAC1 receptor.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA3-113 detects VPAC1 Receptor in human samples.
PA3-113 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry (paraffin) procedures. By Western blot, this antibody detects an ~55-70 kDa protein representing VPAC1 Receptor in human samples. In immunohistochemistry, VPAC1 Receptor immunoreactivity is predominantly localized at the level of the plasma membrane.
PA3-113 immunizing peptide corresponds to amino acid residues 438-457 from human VPAC1 Receptor.
Target Information
The Vasoactive Intestinal Polypeptide Receptor 1 (VPAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Pacap receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; pituitary adenylate cyclase activating polypeptide receptor, type II; Pituitary adenylate cyclase-activating polypeptide type II receptor; Pvr2; type 1 vasoactive intestinal peptide receptor; unnamed protein product; Vasoactive intestinal polypeptide receptor 1; VIP and PACAP receptor 1; VIP receptor 1; VIP receptor subtype 1; VIP receptor, type I; VIP-R-1; VIP1 receptor; VIPR1; VPAC1 receptor; VPAC1R
Gene Aliases: AV071699; HVR1; II; PACAP-R-2; PACAP-R2; RDC1; V1RG; VAPC1; VIP-R-1; VIP-R1; VIPR; VIPR1; VIRG; VPAC1; VPAC1R; VPCAP1R
UniProt ID: (Human) P32241, (Mouse) P97751
Entrez Gene ID: (Human) 7433, (Mouse) 22354
pituitary adenylate cyclase-activating polypeptide receptor activity
transmembrane signaling receptor activity
G-protein coupled receptor activity
vasoactive intestinal polypeptide receptor activity
protein binding
G-protein coupled peptide receptor activity
peptide hormone binding
signal transducer activity
transmembrane signal receptor
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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