Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: VPS37A.
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ESCRT-I complex subunit VPS37A; Hepatocellular carcinoma-related protein 1; hVps37A; polyglutamine binding protein 2; vacuolar protein sorting 37 homolog A; vacuolar protein sorting 37A; Vacuolar protein sorting-associated protein 37A; Vps37A
Gene Aliases: 2210018P21Rik; 4930592A21Rik; AW261445; D8Ertd531e; HCRP1; PQBP2; SPG53; VPS37A