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          • Primary Antibodies ›
          • WDR45 Antibodies

          Proteintech

          WDR45 Polyclonal Antibody

          7 References
          View all (4) WDR45 antibodies

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          Cite WDR45 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (6)
          WDR45 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          WDR45 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          WDR45 Antibody (19194-1-AP) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed HeLa cells using (Product # 19194-1-AP) (WDR45 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          WDR45 Antibody in Immunocytochemistry (ICC/IF)
          WDR45 Antibody in Immunocytochemistry (ICC/IF)
          WDR45 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          WDR45 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          WDR45 Antibody in Western Blot (WB)
          WDR45 Antibody in Western Blot (WB)
          WDR45 Polyclonal Antibody

          Product Details

          19194-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 6 publications 6 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          WDR45 Fusion Protein Ag6741 (1-360 aa encoded by BC000464)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Amount

          45 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MTQQPLRGV TSLRFNQDQS CFCCAMETGV RIYNVEPLME KGHLDHEQVG SMGLVEMLHR SNLLALVGGG SSPKFSEISV LIWDDAREGK DSKEKLVLEF TFTKPVLSVR MRHDKIVIVL KNRIYVYSFP DNPRKLFEFD TRDNPKGLCD LCPSLEKQLL VFPGHKCGSL QLVDLASTKP GTSSAPFTIN AHQSDIACVS LNQPGTVVAS ASQKGTLIRL FDTQSKEKLV ELRRGTDPAT LYCINFSHDS SFLCASSDKG TVHIFALKDT RLNRRSALAR VGKVGPMIGQ YVDSQWSLAS FTVPAESACI CAFGRNTSKN VNSVIAICVD GTFHKYVFTP DGNCNREAFD VYLDICDDDD F (1-360 aa encoded by BC000464)

          Target Information

          This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: JM5; neurodegeneration with brain iron accumulation 4; neurodegeneration with brain iron accumulation 5; unnamed protein product; WD repeat domain phosphoinositide-interacting protein 4; WD repeat domain X-linked 1; WD repeat domain, X-linked 1; WD repeat-containing protein 45; WD-repeat protein; 7-bladed beta-propeller; JM5 protein; WDRX1; WD45 repeat protein interacting with phosphoinositides 4; WIPI-4

          View more View less

          Gene Aliases: C79260; DXImx38e; JM5; NBIA4; NBIA5; Sfc19; WDR45; WDRX1; WDRXI4; WIPI-4; WIPI4

          View more View less

          UniProt ID: (Human) Q9Y484, (Mouse) Q91VM3

          View more View less

          Entrez Gene ID: (Human) 11152, (Mouse) 54636

          View more View less

          Function(s)
          protein binding lipid binding protein kinase binding protein binding, bridging phosphatidylinositol-3-phosphate binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol phosphate binding
          Process(es)
          autophagosome assembly mitophagy pexophagy autophagy cellular response to starvation protein localization to pre-autophagosomal structure nucleophagy glycophagy positive regulation of autophagosome assembly protein lipidation cellular response to nitrogen starvation
          It has to be done as per old AB suggested Products section.

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