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Product Details
PA5-21082
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1 µg/mL | - |
Immunohistochemistry (IHC) |
2.5 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A 17 amino acid peptide near the carboxy terminus of human TFF3. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS |
Contains |
0.02% sodium azide |
Storage conditions |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C |
RRID |
AB_11154149 |
Product Specific Information
A suggested positive control is rat lung tissue lysate.
PA5-21082 can be used with blocking peptide PEP-1196.
Target Information
WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wiz; widely-interspaced zinc finger motifs; Widely-interspaced zinc finger-containing protein; WIZ zinc finger; Zinc finger protein 803
Gene Aliases: WIZ; ZNF803
UniProt ID: (Human) O95785, (Mouse) O88286
Entrez Gene ID: (Human) 58525, (Rat) 314598, (Mouse) 22404
Molecular Function:
C2H2 zinc finger transcription factor
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