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Bioss
WNK3 protein Polyclonal Antibody
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Product Details
BS-1945R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human WNK3 protein, amino acids 451-550.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
WNK3 is a serine/threonine kinase involved in signal transduction and cellular communication. Members of the 'with no lysine' kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PRKWNK 3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3; Serine/threonine-protein kinase WNK3; WNK 3; WNK lysine deficient protein kinase 3, pseudogene
Gene Aliases: KIAA1566; PRKWNK3; RGD1563131; WNK3; Wnk3-ps
UniProt ID: (Human) Q9BYP7, (Mouse) Q80XP9
Entrez Gene ID: (Human) 65267, (Mouse) 279561, (Rat) 317420
protein phosphorylation
positive regulation of sodium ion transport
positive regulation of peptidyl-threonine phosphorylation
positive regulation of ion transmembrane transporter activity
intracellular signal transduction
negative regulation of apoptotic process
protein autophosphorylation
positive regulation of calcium ion transport
positive regulation of establishment of protein localization to plasma membrane
negative regulation of pancreatic juice secretion
regulation of ion homeostasis
positive regulation of sodium ion transmembrane transporter activity
positive regulation of rubidium ion transport
positive regulation of rubidium ion transmembrane transporter activity
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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