In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant mouse (rm) Wnt-1, rmWnt-3A, rmWnt-4, rmWnt-5A, and rmWnt-10B is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
WNT8A, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
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Protein Aliases: Protein Wnt-8a; Protein Wnt-8d; Stimulated by retinoic acid gene 11 protein; wingless-related MMTV integration site 8A; wingless-related MMTV integration site 8D; wnt-8
Gene Aliases: Stra11; Wnt-8A; Wnt-8D; Wnt8a; Wnt8d
UniProt ID: (Mouse) Q64527
Entrez Gene ID: (Mouse) 20890
Molecular Function: intercellular signal molecule