Invitrogen

XDH Polyclonal Antibody

Product Image Gallery

XDH Antibody in Western Blot (WB) — Western Blot analysis of XDH in extracts of mouse liver using XDH Polyclonal Antibody (Product # PA5-88946) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2000

Product Specifications

Species Reactivity

Mouse

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human XDH

Conjugate

Unconjugated

Form

liquid

Concentration

3.42 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2805243

Product Specific Information

Immunogen sequence: MTADKLVFFV NGRKVVEKNA DPETTLLAYL RRKLGLSGTK LGCGEGGCGA CTVMLSKYDR LQNKIVHFSA NACLAPICSL HHVAVTTVEG IGSTKTRLHP VQERIAKSHG SQCGFCTPGI VMSMYTLLRN QPEPTMEEIE NAFQGNLCRC TGYRPILQGF RTFARDGGCC GGDGNNPNCC MNQKKDHSVS LSPSLFKPEE FTPLDPTQEP IFPPELLRLK DTPRKQLRFE GERVTWIQAS TLKELLDLKA QHPDAKLVVG NTEIGIEMKF KNMLFPMIVC; Positive Samples: Mouse liver; Cellular Location: Cytoplasm, Peroxisome

Target Information

XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this antibody

Bioinformatics

Protein Aliases: Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase; Xanthine oxidase; Xanthine oxidoreductase; XD; xdh antibody; xdha antibody; XO; XOR; xor antibody

Gene Aliases: Xdh; XO; Xor; Xox-1; Xox1

UniProt ID: (Mouse) Q00519

Entrez Gene ID: (Mouse) 22436

Molecular Function: dehydrogenase oxidase oxidoreductase