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Invitrogen
XIAP Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-95005
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human XIAP (14-34aa ADINKEEEFVEEFNRLKTFAN).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL once reconstituted
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whole cell, human Raji whole cell, rat C6 whole cell, mouse Neuro-2a whole cell. IHC: Human Intestinal Cancer Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: apoptosis inhibitor protein 3; baculoviral IAP repeat-containing 4; baculoviral IAP repeat-containing protein 4; BIR4; HILP; IAP homolog A; IAP-3; IAP-like protein 1; IAP3; inhibitor of apoptosis protein 3; RIAP-3; RING-type E3 ubiquitin transferase XIAP; RP1-315G1.5; unnamed protein product; X-linked IAP; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
Gene Aliases: 1110015C02Rik; Aipa; API3; BIRC4; hIAP-3; hIAP3; IAP-3; IAP3; ILP-1; ILP1; MIHA; riap3; XLP2
UniProt ID: (Human) P98170, (Mouse) Q60989, (Rat) Q9R0I6
Entrez Gene ID: (Human) 331, (Mouse) 11798, (Rat) 63879
ubiquitin-protein transferase activity
cysteine-type endopeptidase inhibitor activity
protein binding
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
ubiquitin protein ligase activity
protein serine/threonine kinase binding
protease binding
scaffold protein binding
cellular response to DNA damage stimulus
negative regulation of tumor necrosis factor-mediated signaling pathway
regulation of BMP signaling pathway
positive regulation of protein ubiquitination
positive regulation of type I interferon production
response to lipopolysaccharide
defense response to bacterium
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of innate immune response
positive regulation of JNK cascade
regulation of inflammatory response
regulation of cell cycle
copper ion homeostasis
regulation of apoptosis involved in tissue homeostasis
regulation of nucleotide-binding oligomerization domain containing signaling pathway
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
protein K63-linked ubiquitination
positive regulation of canonical Wnt signaling pathway
positive regulation of protein linear polyubiquitination
negative regulation of neuron apoptotic process
neuron apoptotic process
cellular response to hydrogen peroxide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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