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NeoBiotechnologies
Y14/RBM8A Monoclonal Antibody (PCRP-RBM8A-1B4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
9939-MSM2-P1
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PCRP-RBM8A-1B4
Immunogen
Recombinant full-length human RBM8A protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: binder of ovarian cancer 1 protein BOV-1; binder of OVCA1; binder of OVCA1-1; BOV-1; BOV1; BOV1A; BOV1B; BOV1C; exon junction complex core component Y14; RBM8A; ribonucleoprotein RBM8; ribonucleoprotein RBM8A; rna-binding; RNA-binding protein Y14; unnamed protein product
Gene Aliases: BOV-1A; BOV-1B; BOV-1C; C1DELq21.1; DEL1q21.1; MDS014; RBM8; TAR; Y14; ZNRP; ZRNP1
UniProt ID: (Human) Q9Y5S9
Entrez Gene ID: (Human) 9939
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
RNA processing
mRNA export from nucleus
RNA splicing
mRNA metabolic process
regulation of mRNA processing
regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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